Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620470 | 0.87 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPK1MAPTLMNA | |
| SCHEMBL9811375 | 0.82 | KMT2A (0.46) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL10649978 | 0.80 | MAPK1 (0.46) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL10654440 | 0.78 | MAPK1 (0.45) | ALDH1A1MAPK1MAPTGAAPKM | |
| SCHEMBL10873353 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9811288 | 0.76 | KMT2A (0.44) | ALDH1A1KDM4EMAPK1MAPTLMNA | |
| SCHEMBL9811304 | 0.75 | KMT2A (0.43) | KDM4EMAPTLMNAGAASMN1; SMN2 | |
| Oxalic Acid SCHEMBL9811310 | 0.75 | KMT2A (0.43) | ALDH1A1KDM4EMAPK1MAPTLMNA | |
| SCHEMBL9811328 | 0.71 | KMT2A (0.43) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL9620317 | 0.69 | PKM (0.56) | ALDH1A1KDM4EMAPK1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223124-B1 | SUBSTITUTED AMINOSULFONYL 6-NITROBENZOIC-ESTERS OR AMIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1991-06-12 | — | — | EP | claimed |