Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | SHBG | P04278 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949838 | 0.84 | NR3C1 (0.69) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL10495847 | 0.82 | NR3C1 (0.57) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL9811453 | 0.81 | PGR (0.49) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL9811376 | 0.80 | PGR (0.45) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL9019768 | 0.79 | PGR (0.68) | PGRNR3C1CYP3A4AR | |
| SCHEMBL8768805 | 0.79 | PGR (0.55) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL7864495 | 0.79 | PGR (0.47) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL6140132 | 0.75 | PGR (0.50) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL9811526 | 0.75 | LMNA (0.30) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL8541047 | 0.75 | PGR (0.48) | PGRNR3C1CYP3A4ABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277089-B1 | 11-BETA-ALKYNYL ESTRENES AND ESTRADIENES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-06-12 | — | — | EP | disclosed |
| US-4870069-A | POST-COITAL FERTILITY CONTROL | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| EP-0277089-A1 | 11-Beta-alkynyl estrenes and estradienes, their preparations and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-08-03 | — | — | EP | disclosed |