Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.32 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601026 | 0.82 | POLB (0.50) | POLBRECQLESR2CYP3A4CYP2D6 | |
| SCHEMBL6839192 | 0.81 | POLB (0.49) | POLBRECQLESR2CYP3A4CYP2D6 | |
| SCHEMBL447196 | 0.80 | POLB (0.48) | POLBRECQLESR2CYP3A4CYP2D6 | |
| SCHEMBL6840086 | 0.80 | POLB (0.48) | POLBRECQLESR2CYP3A4CYP2D6 | |
| SCHEMBL6839421 | 0.79 | POLB (0.52) | POLBRECQLESR2CYP3A4CYP2D6 | |
| SCHEMBL9812265 | 0.78 | PDIA6 (0.43) | POLBRECQLESR2TDP1 | |
| SCHEMBL1803308 | 0.76 | POLB (0.52) | POLBRECQLESR2TDP1CDC25A | |
| SCHEMBL1803306 | 0.76 | POLB (0.52) | POLBRECQLESR2CYP3A4CYP2D6 | |
| SCHEMBL1309212 | 0.75 | POLB (0.55) | POLBRECQLESR2IDH1CDC25A | |
| SCHEMBL9145771 | 0.75 | NR3C1 (0.33) | POLBRECQLCYP3A4CYP2D6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225728-B1 | LIQUID CRYSTALLINE CARBONIC ACID ESTER AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | Chisso Corporation (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0225728-A2 | Liquid crystalline carbonic acid ester and liquid crystal composition containing same | Chisso Corporation (JP) | 1987-06-16 | — | — | EP | disclosed |