Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDIA6 | Q15084 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812259 | 0.78 | POLB (0.44) | TDP1POLBRECQLESR2 | |
| SCHEMBL9812267 | 0.74 | MEN1 (0.42) | MEN1KMT2ATDP1TSHRSMN1; SMN2 | |
| SCHEMBL4535304 | 0.73 | PDIA6 (0.62) | PDIA6MEN1KMT2APPARGPPARA | |
| SCHEMBL4532951 | 0.71 | PDIA6 (0.63) | PDIA6MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9146689 | 0.71 | NPC1 (0.44) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL20326392 | 0.71 | CA12 (0.47) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL9146695 | 0.71 | NPC1 (0.44) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL6939838 | 0.70 | LTA4H (0.58) | MEN1KMT2ATDP1ESR2 | |
| SCHEMBL9509683 | 0.70 | LTA4H (0.58) | MEN1KMT2ATDP1ESR2 | |
| SCHEMBL8300776 | 0.70 | POLB (0.49) | ALDH1A1L3MBTL1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225728-B1 | LIQUID CRYSTALLINE CARBONIC ACID ESTER AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | Chisso Corporation (JP) | 1991-07-03 | — | — | EP | disclosed |
| US-4759869-A | Carbonic acid ester containing assymetrical carbon atom and benzene rings | CHISSO CORPORATION (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0225728-A2 | Liquid crystalline carbonic acid ester and liquid crystal composition containing same | Chisso Corporation (JP) | 1987-06-16 | — | — | EP | disclosed |