Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812947 | 0.90 | TBXA2R (0.65) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL9813009 | 0.87 | TBXA2R (0.63) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL9813021 | 0.86 | ALDH1A1 (0.62) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL9813027 | 0.83 | TBXAS1 (0.51) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL9813017 | 0.83 | TBXA2R (0.75) | ALDH1A1TBXAS1TBXA2RPPARGPPARA | |
| SCHEMBL13889020 | 0.83 | ALDH1A1 (0.69) | ALDH1A1TPSAB1POLBHTR7CYP19A1 | |
| SCHEMBL10772979 | 0.80 | TBXA2R (0.57) | TBXAS1TBXA2RPPARGPPARAAKR1C3 | |
| SCHEMBL9128686 | 0.79 | TBXA2R (0.62) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL9127503 | 0.79 | TBXA2R (0.69) | CA12CA1CA2CA4CA9 | |
| SCHEMBL9129388 | 0.79 | TBXA2R (0.62) | ALDH1A1CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223593-B1 | PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1991-08-07 | — | — | EP | claimed |
| EP-0223593-A2 | Phenoxyalkylcarboxylic acids and esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | claimed |
| EP-0223593-B1 | PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1991-08-07 | — | — | EP | disclosed |
| EP-0223593-A2 | Phenoxyalkylcarboxylic acids and esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | disclosed |