Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 3/20 | 0.49 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | GMPS | P49915 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10513954 | 0.79 | DDB1 (0.36) | PDE4DPDE3A | |
| SCHEMBL9446941 | 0.78 | ADORA2A (0.43) | AHCYPRMT5WDR77ADORA2AADORA3 | |
| SCHEMBL8094883 | 0.76 | ADORA2A (0.50) | AHCYDOT1LPRMT5WDR77ADORA2A | |
| SCHEMBL10427714 | 0.74 | ADORA2A (0.50) | AHCYDOT1LPRMT5WDR77ADORA2A | |
| SCHEMBL5180860 | 0.73 | ADORA2A (0.49) | AHCYDOT1LPRMT5WDR77ADORA2A | |
| SCHEMBL4745239 | 0.73 | PI4K2A (0.52) | AHCYPRMT5WDR77ADORA2AADORA3 | |
| SCHEMBL27730982 | 0.71 | SLC28A1 (0.49) | AHCYDOT1LADORA2AADORA3SLC28A1 | |
| SCHEMBL8704526 | 0.70 | AHCY (0.47) | AHCYDOT1LADORA2AADORA3SLC28A1 | |
| SCHEMBL2952014 | 0.69 | SLC28A1 (0.48) | DOT1LADORA2AADORA3SLC28A1PI4KA | |
| SCHEMBL5860316 | 0.69 | AHCY (0.56) | AHCYDOT1LADORA2API4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437469-A1 | NUCLEOSIDE DERIVATIVES | NYCOMED AS (NO) | 1991-07-24 | — | — | EP | disclosed |
| WO-1990004602-A1 | NUCLEOSIDE DERIVATIVES | NYCOMED AS (NO) | 1990-05-03 | — | — | WO | disclosed |
| EP-0362967-A1 | Nucleoside derivatives | NYCOMED IMAGING AS (NO) | 1990-04-11 | — | — | EP | disclosed |