Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707052 | 0.89 | ACE (0.46) | ACEALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9707114 | 0.83 | ALDH1A1 (0.50) | ACEALDH1A1MAPK1L3MBTL1KLK5 | |
| SCHEMBL9707090 | 0.81 | LMNA (0.44) | ACEALDH1A1MAPK1L3MBTL1KLK5 | |
| SCHEMBL9707085 | 0.76 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL10756387 | 0.74 | LTA4H (0.56) | ACEALDH1A1MAPK1L3MBTL1KLK5 | |
| SCHEMBL10508472 | 0.74 | ACE (0.62) | ACEALDH1A1MAPK1L3MBTL1KLK5 | |
| SCHEMBL10508467 | 0.74 | ACE (0.62) | ACEALDH1A1MAPK1L3MBTL1KLK5 | |
| SCHEMBL9510615 | 0.73 | SMN1; SMN2 (0.53) | ALDH1A1L3MBTL1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL11154974 | 0.73 | ACE (0.64) | ACEALDH1A1MAPK1L3MBTL1KLK5 | |
| Hydrochloric Acid SCHEMBL9513854 | 0.73 | SMN1; SMN2 (0.52) | ALDH1A1L3MBTL1SMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981853-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | G. D. SEARLE & CO. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4959364-A | Method of treating inflammation, allergy, asthma and proliferative skin disease using heterocyclic amides | G. D. SEARLE & CO. (US) | 1990-09-25 | — | — | US | disclosed |