Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015491 | 0.90 | OPRK1 (0.38) | POLBALDH1A1L3MBTL1 | |
| SCHEMBL9816342 | 0.88 | LMNA (0.40) | POLBGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10879172 | 0.77 | ALDH1A1 (0.38) | POLBGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL9816287 | 0.74 | LMNA (0.44) | POLBSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL9816330 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL7423312 | 0.70 | ALDH1A1 (0.49) | POLBGAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL27056823 | 0.69 | MAOB (0.46) | POLBSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL10878174 | 0.68 | TACR1 (0.48) | POLBGAARAB9AL3MBTL1 | |
| SCHEMBL10875499 | 0.68 | L3MBTL1 (0.59) | LMNAL3MBTL1KMT2A | |
| SCHEMBL983419 | 0.67 | ALDH1A1 (0.62) | POLBSMN1; SMN2ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153992-B1 | WATER SOLUBLE DERIVATIVES OF 3,5-DIACETO AMIDO-2,4,6-TRIIODOBENZOIC ACID AND PROCESS FOR THEIR PREPARATION AND USE | Dr. Franz Köhler Chemie GmbH (DE) | 1991-10-16 | — | — | EP | disclosed |