Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816285 | 0.88 | POLB (0.36) | LMNASMN1; SMN2POLBGAAALDH1A1 | |
| SCHEMBL11015491 | 0.86 | OPRK1 (0.38) | POLBALDH1A1L3MBTL1 | |
| SCHEMBL7423312 | 0.81 | ALDH1A1 (0.49) | SMN1; SMN2POLBGAAALDH1A1TDP1 | |
| SCHEMBL10879172 | 0.78 | ALDH1A1 (0.38) | LMNASMN1; SMN2POLBGAAALDH1A1 | |
| SCHEMBL9816280 | 0.72 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL11622271 | 0.71 | ALDH1A1 (0.56) | LMNASMN1; SMN2POLBGAAALDH1A1 | |
| SCHEMBL28408225 | 0.71 | EPHX2 (0.54) | SMN1; SMN2POLBGAAALDH1A1TDP1 | |
| SCHEMBL9816351 | 0.70 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9816331 | 0.70 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL983419 | 0.70 | ALDH1A1 (0.62) | SMN1; SMN2POLBALDH1A1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153992-B1 | WATER SOLUBLE DERIVATIVES OF 3,5-DIACETO AMIDO-2,4,6-TRIIODOBENZOIC ACID AND PROCESS FOR THEIR PREPARATION AND USE | Dr. Franz Köhler Chemie GmbH (DE) | 1991-10-16 | — | — | EP | disclosed |