Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27506588 | 0.80 | CA12 (0.47) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL27488751 | 0.80 | HDAC3 (0.47) | PPARGPPARAALDH1A1MAPTKMT2A | |
| SCHEMBL27487295 | 0.80 | LMNA (0.48) | ALDH1A1LMNAKMT2AHSD17B10TSHR | |
| SCHEMBL27488015 | 0.78 | SLC1A1 (0.43) | PPARGPPARAKMT2AMAOA | |
| SCHEMBL27505825 | 0.78 | PNMT (0.48) | ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL2368827 | 0.76 | BDKRB2 (0.53) | GRIN2DGRIN2AGRIN2BGRIN2CCYP1A2 | |
| SCHEMBL22256182 | 0.74 | HTR2A (0.51) | PPARGPPARAKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9816446 | 0.74 | ALDH1A1 (0.53) | PPARGPPARAALDH1A1CYSLTR2CYSLTR1 | |
| SCHEMBL31650453 | 0.74 | LDHA (0.54) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL21617914 | 0.72 | LMNA (0.60) | ALDH1A1LMNAMAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174271-B1 | ANTHRACEME DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| EP-0174271-A2 | Anthraceme derivatives | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |