Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | SI | P14410 | 4/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816989 | 0.93 | LTA4H (0.40) | HDAC8PDK2LTA4HESR1MEN1 | |
| SCHEMBL9817134 | 0.92 | CNR1 (0.41) | HDAC8PDK2LTA4HESR1MEN1 | |
| SCHEMBL9816992 | 0.91 | HDAC8 (0.41) | HDAC8PDK2LTA4HALDH1A1MEN1 | |
| SCHEMBL9816984 | 0.91 | LMNA (0.42) | PDK2LTA4HESR1ALDH1A1LMNA | |
| SCHEMBL9713951 | 0.88 | KIF11 (0.47) | ESR1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9713613 | 0.88 | THRA (0.39) | LTA4HESR1NPC1RAB9ABACE1 | |
| SCHEMBL2867989 | 0.87 | BACE1 (0.44) | ESR1ALDH1A1BACE1 | |
| SCHEMBL9817117 | 0.86 | HDAC8 (0.42) | HDAC8PDK2LTA4HALDH1A1MEN1 | |
| SCHEMBL9817130 | 0.85 | ESR1 (0.46) | HDAC8PDK2LTA4HESR1ALDH1A1 | |
| SCHEMBL9817071 | 0.84 | LMNA (0.41) | LTA4HESR1ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277627-B1 | POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-10-23 | — | — | EP | disclosed |
| US-4801679-A | Polyformal resin and process for producing said resin | IDEMITSU KOSAN CO., LTD. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0277627-A1 | Polyformal resins and process for producing said resins | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |