Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713939 | 0.93 | KIF11 (0.51) | KIF11KCNH2BACE1CNR1CNR2 | |
| SCHEMBL9713821 | 0.91 | CNR1 (0.50) | KIF11KCNH2BACE1CNR1CNR2 | |
| SCHEMBL9713613 | 0.90 | THRA (0.39) | KIF11KCNH2BACE1CNR1CNR2 | |
| SCHEMBL9713890 | 0.90 | BACE1 (0.48) | KIF11KCNH2BACE1CNR1CNR2 | |
| SCHEMBL2867989 | 0.89 | BACE1 (0.44) | KIF11BACE1CNR1CNR2ALDH1A1 | |
| SCHEMBL9816984 | 0.89 | LMNA (0.42) | KIF11BACE1CNR1CNR2KDM4E | |
| SCHEMBL9817030 | 0.88 | HDAC8 (0.40) | BACE1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9817109 | 0.85 | KIF11 (0.47) | KIF11KCNH2BACE1CNR1CNR2 | |
| SCHEMBL9816997 | 0.82 | LTA4H (0.42) | KIF11KCNH2BACE1CNR1CNR2 | |
| SCHEMBL9817071 | 0.81 | LMNA (0.41) | KIF11KCNH2CNR1CNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151531-A | DIHYDRIC PHENOLS | IDEMITSU KOSAN CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0249963-B1 | POLYCARBONATES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-04-22 | — | — | EP | disclosed |
| EP-0277627-B1 | POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-10-23 | — | — | EP | disclosed |
| US-4892924-A | Polycarbonate containing compound from bis(3-phenyl-4-hydroxyphenyl) | IDEMITSU KOSAN CO., LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| US-4801679-A | Polyformal resin and process for producing said resin | IDEMITSU KOSAN CO., LTD. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0277627-A1 | Polyformal resins and process for producing said resins | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |
| EP-0249963-A2 | Polycarbonates | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-12-23 | — | — | EP | disclosed |