Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817255 | 0.82 | MEN1 (0.40) | ALDH1A1SMN1; SMN2GPR35HPGDMAPK1 | |
| SCHEMBL3026826 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HPGDMAPK1KMT2A | |
| SCHEMBL9817283 | 0.81 | ITGA4 (0.41) | ALDH1A1SMN1; SMN2GPR35TP53HPGD | |
| SCHEMBL9817323 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2GPR35TP53HPGD | |
| SCHEMBL9817230 | 0.77 | L3MBTL1 (0.49) | ALDH1A1SMN1; SMN2HPGDTSHRGAA | |
| SCHEMBL31324800 | 0.76 | PTGDR2 (0.62) | PTGDR2ALDH1A1SMN1; SMN2GPR35TP53 | |
| SCHEMBL9817335 | 0.75 | PTGDR2 (0.39) | PTGDR2ALDH1A1SMN1; SMN2GPR35TP53 | |
| SCHEMBL10788795 | 0.73 | LMNA (0.49) | ALDH1A1SMN1; SMN2TSHRKMT2AGAA | |
| SCHEMBL27456246 | 0.71 | MAPT (0.50) | PTGDR2ALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL11310846 | 0.71 | MEN1 (0.42) | ALDH1A1SMN1; SMN2GPR35TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248213-B1 | HYDROXYPHENYL- AND HYDROXYPHENOXYALKANOIC ACID IODOPROPARGYL ESTERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-4731466-A | FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0248213-A2 | Hydroxyphenyl- and hydroxyphenoxyalkanoic acid iodopropargyl esters | THE DOW CHEMICAL COMPANY (US) | 1987-12-09 | — | — | EP | disclosed |