Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817552 | 0.85 | POLB (0.37) | MTNR1AMTNR1BHDAC8NPC1TSHR | |
| SCHEMBL2778925 | 0.84 | HDAC8 (0.34) | HDAC8AKR1B10AKR1B1NPC1RAB9A | |
| SCHEMBL22549024 | 0.79 | NPC1 (0.36) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL22451189 | 0.76 | APP (0.34) | AKR1B10AKR1B1APPNPC1RAB9A | |
| SCHEMBL8397405 | 0.75 | KDM4E (0.35) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL13483389 | 0.75 | NPC1 (0.39) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL22549036 | 0.72 | NPC1 (0.36) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL20580264 | 0.72 | RAB9A (0.35) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL22549006 | 0.71 | THRB (0.41) | NPC1TSHRRAB9AMAPTKDM4E | |
| SCHEMBL7739362 | 0.71 | AKR1B10 (0.37) | AKR1B10AKR1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274844-B1 | ULTRAVIOLET ABSORBING POLYMERS COMPRISING 2-(2'-HYDROXY 5'-ACRYLOYLOXYALKOXYPHENYL)-2H-BENZOTRIAZOLE | IOLAB CORPORATION (US) | 1991-11-06 | — | — | EP | claimed |