Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182778 | 0.77 | ALDH1A1 (0.42) | TSHRTHRBALDH1A1ALOX12HTT | |
| SCHEMBL28013355 | 0.75 | THRB (0.40) | TSHRTHRBSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9302812 | 0.74 | THRB (0.49) | TSHRTHRBALDH1A1ALOX12HTT | |
| SCHEMBL28139081 | 0.72 | TSHR (0.44) | TSHRTHRBADRB2ADRB1ADRB3 | |
| SCHEMBL7470086 | 0.72 | POLB (0.44) | THRBSLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL12573379 | 0.71 | KDM4E (0.57) | ADRB2ADRB1ADRB3ALDH1A1KMT2A | |
| SCHEMBL10492073 | 0.71 | GAA (0.41) | ADRB2ADRB1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27738550 | 0.71 | POLB (0.43) | THRBSLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL11580098 | 0.71 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1ALDH1A1ALOX12 | |
| SCHEMBL6390791 | 0.70 | RAPGEF4 (0.40) | TSHRSLC1A3SLC1A2SLC1A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460026-A1 | HIGH PERFORMANCE AFFINITY CHROMATOGRAPHY COLUMN COMPRISING NON-POROUS, MONODISPERSE POLYMERIC PACKING MATERIAL | EASTMAN KODAK COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| WO-1990009832-A1 | HIGH PERFORMANCE AFFINITY CHROMATOGRAPHY COLUMN COMPRISING NON-POROUS, MONODISPERSE POLYMERIC PACKING MATERIAL | EASTMAN KODAK COMPANY (US) | 1990-09-07 | — | — | WO | disclosed |