SCHEMBL9818017

SCHEMBL9818017

C=CCN1C(=O)C(C)=C(C)C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.47
CYP3A4 P08684 1/20 0.44
MAPT P10636 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 4/20 0.40
PKM P14618 2/20 0.40
KMT2A Q03164 6/20 0.39
MEN1 O00255 5/20 0.39
KDM4E B2RXH2 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
HTT P42858 1/20 0.39
POLB P06746 2/20 0.39
RXFP1 Q9HBX9 1/20 0.39
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 1/20 0.34
CYP1A2 P05177 1/20 0.34
MYC P01106 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7038598 0.84 CASP3 (0.54) CASP3CYP3A4MAPTL3MBTL1ALDH1A1
SCHEMBL11306231 0.75 CASP3 (0.47) CASP3CYP3A4MAPTL3MBTL1ALDH1A1
SCHEMBL17835468 0.74 CYP3A4 (0.48) CASP3CYP3A4MAPTL3MBTL1ALDH1A1
SCHEMBL26626010 0.73 ALDH1A1 (0.44) ALDH1A1PKMSMN1; SMN2
SCHEMBL12180545 0.72 MEN1 (0.38) CASP3CYP3A4MAPTL3MBTL1ALDH1A1
SCHEMBL11167868 0.72 ALDH1A1 (0.42) CASP3MAPTALDH1A1PKMKMT2A
SCHEMBL8443692 0.72 CASP3 (0.44) CASP3CYP3A4MAPTL3MBTL1ALDH1A1
SCHEMBL15046563 0.71 CASP3 (0.56) CASP3CYP3A4L3MBTL1ALDH1A1KMT2A
SCHEMBL10860362 0.70 ALDH1A1 (0.44) ALDH1A1PKM
SCHEMBL7035794 0.70 MGLL (0.46) CASP3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11982942-B2 Positive tone photoresist formulation using crosslinkable siloxane compounds MERCK PATENT GMBH (DE) 2024-05-14 US disclosed
US-20240053681-A1 POSITIVE TONE PHOTORESIST FORMULATION USING CROSSLINKABLE SILOXANE COMPOUNDS MERCK PATENT GMBH (DE) 2024-02-15 US disclosed
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound SHIKOKU CHEMICALS CORPORATION (JP) 2023-10-03 US disclosed
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound SHIKOKU CHEMICALS CORPORATION (JP) 2023-10-03 US disclosed
CN-113508152-B Crosslinkable silicone compounds for producing dielectric materials 默克专利股份有限公司 2023-08-08 CN disclosed
US-20220177651-A1 CROSSLINKABLE SILOXANE COMPOUNDS FOR THE PREPARATION OF DIELECTRIC MATERIALS MERCK PATENT GMBH (DE) 2022-06-09 US disclosed
US-20220177651-A1 CROSSLINKABLE SILOXANE COMPOUNDS FOR THE PREPARATION OF DIELECTRIC MATERIALS MERCK PATENT GMBH (DE) 2022-06-09 US disclosed
CN-114503031-A Positive photoresist formulation using crosslinkable siloxane compounds 默克专利股份有限公司 2022-05-13 CN disclosed
CN-113508152-A Crosslinkable siloxane compounds for producing dielectric materials 默克专利股份有限公司 2021-10-15 CN disclosed
WO-2020182636-A1 CROSSLINKABLE SILOXANE COMPOUNDS FOR THE PREPARATION OF DIELECTRIC MATERIALS MERCK PATENT GMBH (DE) 2020-09-17 WO disclosed
US-4604437-A Polymer from substituted, unsaturated, bicyclic imide CIBA-GEIGY CORPORATION (US) 1986-08-05 US disclosed
US-4565873-A ADHESION PROMOTERS CIBA-GEIGY CORPORATION (US) 1986-01-21 US disclosed
EP-0105024-B1 UNSATURATED SUBSTITUTED BICYCLIC IMIDES AND THEIR POLYMERS CIBA-GEIGY AG (CH) 1985-10-30 EP disclosed
EP-0152372-A2 Substituted unsaturated bicyclic imides and their polymers CIBA-GEIGY AG (CH) 1985-08-21 EP disclosed
US-4515962-A Allyl or methallyl-bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid imides and bisimides CIBA GEIGY CORPORATION (US) 1985-05-07 US disclosed
EP-0105024-A1 Unsaturated substituted bicyclic imides and their polymers CIBA-GEIGY AG (CH) 1984-04-04 EP disclosed
US-4417057-A N-Substituted imides and bis-imides CIBA-GEIGY CORPORATION (US) 1983-11-22 US disclosed
US-4364808-A ADHESION PROMOTERS CIBA-GEIGY CORPORATION (US) 1982-12-21 US disclosed
US-4301075-A CHEMICAL INTERMEDIATES FOR SILICON-MODIFIED ADHESION PROMOTERS CIBA-GEIGY CORPORATION (US) 1981-11-17 US disclosed
US-4271074-A Silanes containing imide groups CIBA-GEIGY CORPORATION (US) 1981-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound TST, TMT1A, CTH CASP3 3645/4885CYP3A4 3062/4885MAPT 1549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.