SCHEMBL981858

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL579200	0.95	XDH (0.41)	MEN1KMT2AKDM4EMAPTMAPK1
	SCHEMBL980438	0.81	XDH (0.41)	XDH
	SCHEMBL1298234	0.78	KDM1A (0.41)	MEN1KMT2AKDM4EMAPTHTT
	SCHEMBL579116	0.78	XDH (0.39)	KDM1AXDH
	SCHEMBL27757234	0.78	HRH3 (0.46)	KDM4EALDH1A1SMN1; SMN2HSD17B10XDH
	SCHEMBL12109144	0.77	MEN1 (0.46)	MEN1KMT2AKDM4EMAPTMAPK1
	SCHEMBL12107218	0.76	XDH (0.43)	KDM1AXDH
	SCHEMBL2885756	0.75	HRH3 (0.41)	XDH
	SCHEMBL14957037	0.75	ALDH1A1 (0.63)	KDM4EMAPTL3MBTL1LMNAALDH1A1
	SCHEMBL10095240	0.74	L3MBTL1 (0.53)	L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.