Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | PTPRG | P23470 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819060 | 1.00 | FFAR1 (0.41) | FFAR1PPARGPPARDSIGMAR1SSTR3 | |
| SCHEMBL9818900 | 0.87 | MAOB (0.41) | FFAR1PPARGPPARD | |
| SCHEMBL9818902 | 0.87 | MAOB (0.41) | FFAR1PPARGPPARD | |
| SCHEMBL9819040 | 0.85 | LTB4R (0.43) | FFAR1PPARGPPARD | |
| SCHEMBL9819044 | 0.85 | LTB4R (0.43) | FFAR1PPARGPPARD | |
| SCHEMBL9818925 | 0.80 | MEN1 (0.48) | FFAR1PPARGPPARD | |
| SCHEMBL9818920 | 0.80 | MEN1 (0.48) | FFAR1PPARGPPARD | |
| SCHEMBL27277358 | 0.77 | CCR2 (0.43) | — | |
| SCHEMBL9819041 | 0.76 | HTT (0.40) | FFAR1PPARGPPARD | |
| SCHEMBL9819039 | 0.76 | HTT (0.40) | FFAR1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230379-B1 | CHROMAN- AND THIOCHROMAN-4-ACETIC ACIDS USEFUL IN THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1991-04-03 | — | — | EP | disclosed |