Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818925 | 1.00 | MEN1 (0.48) | MEN1KMT2APSMB5ALDH1A1FFAR1 | |
| SCHEMBL9819040 | 0.88 | LTB4R (0.43) | MEN1KMT2APSMB5ALDH1A1FFAR1 | |
| SCHEMBL9819044 | 0.88 | LTB4R (0.43) | MEN1KMT2APSMB5ALDH1A1FFAR1 | |
| SCHEMBL9818900 | 0.85 | MAOB (0.41) | FFAR1NPC1RAB9ASMN1; SMN2PPARD | |
| SCHEMBL9818902 | 0.85 | MAOB (0.41) | FFAR1NPC1RAB9ASMN1; SMN2PPARD | |
| SCHEMBL9819065 | 0.80 | FFAR1 (0.41) | FFAR1PPARDPPARG | |
| SCHEMBL9819060 | 0.80 | FFAR1 (0.41) | FFAR1PPARDPPARG | |
| SCHEMBL9819041 | 0.79 | HTT (0.40) | MEN1KMT2AALDH1A1FFAR1HPGD | |
| SCHEMBL9819039 | 0.79 | HTT (0.40) | MEN1KMT2AALDH1A1FFAR1HPGD | |
| SCHEMBL9818756 | 0.77 | HTT (0.42) | MEN1KMT2AALDH1A1FFAR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230379-B1 | CHROMAN- AND THIOCHROMAN-4-ACETIC ACIDS USEFUL IN THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1991-04-03 | — | — | EP | disclosed |