SCHEMBL9818951

SCHEMBL9818951

CC(=O)OC1CCN(Cc2ccccc2)C(OC(C)=O)C1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.44
GBA1 P04062 1/20 0.43
SCN1A P35498 1/20 0.43
SCN2A Q99250 1/20 0.43
SCN3A Q9NY46 1/20 0.43
POLB P06746 1/20 0.42
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7668389 0.85 KDM4E (0.46)
SCHEMBL10518314 0.85 OPRD1 (0.43) BCHEGBA1SCN1ASCN2ASCN3A
SCHEMBL4135213 0.79 BCHE (0.67) BCHE
Hydrochloric Acid SCHEMBL9380707 0.78 BCHE (0.65) BCHE
SCHEMBL9819358 0.77 SIGMAR1 (0.49)
SCHEMBL4752402 0.77 SIGMAR1 (0.51) BCHEPOLB
SCHEMBL2893650 0.77 BCHE (0.60) BCHE
SCHEMBL3206960 0.77 BCHE (0.60) BCHE
SCHEMBL9685669 0.77 BCHE (0.60) BCHE
SCHEMBL2771500 0.76 GBA1 (0.50) BCHEGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0259227-B1 BENZHYDRYLOXYETHYL PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Société anonyme: LES LABORATOIRES MERAM (FR) 1991-12-27 EP disclosed
EP-0259227-A1 Benzhydryloxyethyl piperidine derivatives, process for their preparation and pharmaceutical compositions containing them Société anonyme: LES LABORATOIRES MERAM (FR) 1988-03-09 EP disclosed