Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 8/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819059 | 0.86 | GSTO1 (0.36) | GSTO1ALDH1A1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL9818966 | 0.77 | MCL1 (0.39) | GSTO1MCL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9818956 | 0.71 | PIM1 (0.39) | GSTO1MCL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9819118 | 0.66 | ALDH1A1 (0.33) | GSTO1MCL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9819224 | 0.65 | SMN1; SMN2 (0.49) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9819221 | 0.64 | TSHR (0.39) | GSTO1ALDH1A1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL9577076 | 0.64 | ALDH1A1 (0.52) | GSTO1ALDH1A1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL9819045 | 0.63 | ALDH1A1 (0.35) | GSTO1ALDH1A1MEN1KMT2AKCNJ6 | |
| SCHEMBL11167601 | 0.61 | CA12 (0.62) | GSTO1MCL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9512820 | 0.60 | ALDH1A1 (0.37) | GSTO1MCL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312338-B1 | SULFAMOYL-2-BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-12-27 | — | — | EP | claimed |
| US-4918206-A | DIURETICS, HYPOTENSIVE AGENTS; SIDE EFFECT REDUCTION | SHIONOGI & CO., LTD. (JP) | 1990-04-17 | — | — | US | claimed |
| EP-0312338-B1 | SULFAMOYL-2-BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4918206-A | DIURETICS, HYPOTENSIVE AGENTS; SIDE EFFECT REDUCTION | SHIONOGI & CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0312338-A1 | Sulfamoyl-2-benzofurancarboxylic acid derivatives, their preparation and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1989-04-19 | — | — | EP | disclosed |