Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819413 | 0.82 | TSHR (0.37) | KMT2AGSTO1 | |
| SCHEMBL9819188 | 0.81 | DAO (0.38) | KMT2AGSTO1APP | |
| SCHEMBL9819164 | 0.80 | SMN1; SMN2 (0.43) | KMT2A | |
| SCHEMBL9819205 | 0.74 | TP53 (0.43) | KMT2AAPP | |
| SCHEMBL9819197 | 0.67 | APP (0.40) | KMT2AGSTO1APP | |
| SCHEMBL9819399 | 0.65 | MAPT (0.37) | — | |
| SCHEMBL9577112 | 0.65 | CA1 (0.41) | KMT2AGSTO1 | |
| SCHEMBL11348961 | 0.64 | TDP1 (0.40) | KMT2AGSTO1APP | |
| SCHEMBL9819118 | 0.63 | ALDH1A1 (0.33) | KMT2AGSTO1 | |
| SCHEMBL9818958 | 0.62 | MCL1 (0.40) | KMT2AGSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312338-B1 | SULFAMOYL-2-BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-12-27 | — | — | EP | claimed |