Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15033486 | 0.76 | TSHR (0.61) | HSD17B10GAAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL1280809 | 0.75 | HSD17B10 (0.54) | HSD17B10GAAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL28353455 | 0.73 | TSHR (0.61) | HSD17B10GAAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL28965465 | 0.73 | TSHR (0.61) | HSD17B10GAAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL9819256 | 0.71 | MEN1 (0.47) | HSD17B10SMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL9819404 | 0.71 | MGLL (0.47) | HSD17B10MAPTTSHRHTR1AALDH1A1 | |
| SCHEMBL26098617 | 0.70 | BCHE (0.61) | HSD17B10GAAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL5507874 | 0.70 | SMN1; SMN2 (0.75) | HSD17B10GAAMAPK1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL9819442 | 0.70 | ADRA2C (0.44) | GAASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL7683268 | 0.69 | TSHR (0.51) | HSD17B10SMN1; SMN2MAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |