Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | BCL2A1 | Q16548 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAD51 | Q06609 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | BID | P55957 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | RAD1 | O60671 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028720 | 0.84 | KMT2A (0.53) | KMT2AMEN1BCL2A1MAPTRAD51 | |
| SCHEMBL9819453 | 0.82 | ALDH1A1 (0.49) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL9819370 | 0.81 | KMT2A (0.53) | KMT2AMEN1BCL2A1MAPTALDH1A1 | |
| Dichlorophenyl Succinimide SCHEMBL31196508 | 0.79 | KMT2A (0.57) | KMT2AMEN1BCL2A1MAPTRAD51 | |
| SCHEMBL11656315 | 0.78 | KMT2A (0.53) | KMT2AMEN1BCL2A1MAPTRAD51 | |
| SCHEMBL9819264 | 0.77 | ADRA1B (0.47) | KMT2AMEN1BCL2A1MAPTALDH1A1 | |
| SCHEMBL9819362 | 0.77 | ELANE (0.59) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL9819272 | 0.76 | SLC6A2 (0.56) | KMT2AMEN1SLC6A2SLC6A4HIF1A | |
| SCHEMBL9819285 | 0.76 | FAAH (0.44) | KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10874965 | 0.75 | KMT2A (0.47) | KMT2AMEN1BCL2A1MAPTRAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |