Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 6/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 5/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29695621 | 0.84 | KMT2A (0.37) | OR51E2KMT2AMAPK1HSD11B1TSHR | |
| SCHEMBL31154196 | 0.84 | KMT2A (0.37) | OR51E2KMT2AMAPK1HSD11B1TSHR | |
| SCHEMBL93393 | 0.81 | KMT2A (0.39) | KMT2AMAPK1HSD11B1TSHRHMGCR | |
| SCHEMBL4837194 | 0.81 | KMT2A (0.39) | KMT2AMAPK1HSD11B1TSHRHMGCR | |
| SCHEMBL954279 | 0.79 | LDHA (0.47) | KMT2AEGLN1HSD11B1TSHRHMGCR | |
| SCHEMBL24013363 | 0.78 | KMT2A (0.33) | KMT2A | |
| SCHEMBL9566006 | 0.78 | KMT2A (0.37) | KMT2AMAPK1HSD11B1TSHRHMGCR | |
| SCHEMBL21405194 | 0.78 | KMT2A (0.37) | KMT2AMAPK1HSD11B1TSHRHMGCR | |
| SCHEMBL21002308 | 0.78 | KMT2A (0.37) | KMT2AMAPK1HSD11B1TSHRHMGCR | |
| SCHEMBL15788938 | 0.78 | KMT2A (0.37) | KMT2AMAPK1HSD11B1TSHRHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156456-B1 | ONE-PART ADDITION-CURING HEAT-CONDUCTIVE SILICONE GREASE COMPOSITION | SHINETSU CHEMICAL CO (JP) | 2021-01-20 | — | — | EP | claimed |
| EP-3199591-B1 | UV-THICKENING THERMALLY CONDUCTIVE SILICONE GREASE COMPOSITION | SHINETSU CHEMICAL CO (JP) | 2020-04-29 | — | — | EP | claimed |
| EP-0693473-B1 | Method of producing pivaloylacetic acid ester | UBE INDUSTRIES (JP) | 1998-04-22 | — | — | EP | claimed |
| US-5679830-A | DECARBONYLATION OF PIVALOYLPYRUVIC ACID IN THE PRESENCE OF AN INORGANIC OXIDE CATALYST | UBE INDUSTRIES, LTD. (JP) | 1997-10-21 | — | — | US | claimed |
| EP-0693473-A1 | Method of producing pivaloylacetic acid ester | UBE INDUSTRIES, LTD. (JP) | 1996-01-24 | — | — | EP | claimed |
| US-5449799-A | Compound for depositing copper layers | TERFLOTH CHRISTIAN (DE) | 1995-09-12 | — | — | US | claimed |
| EP-0454843-A4 | METHOD AND APPARATUS FOR THE RAPID DEPOSITION BY CHEMICAL VAPOR DEPOSITION WITH LOW VAPOR PRESSURE REACTANTS | GEORGIA TECH RES INST (US) | 1994-12-28 | — | — | EP | claimed |
| EP-0454843-A1 | METHOD AND APPARATUS FOR THE RAPID DEPOSITION BY CHEMICAL VAPOR DEPOSITION WITH LOW VAPOR PRESSURE REACTANTS | GEORGIA TECH RESEARCH CORPORATION (US) | 1991-11-06 | — | — | EP | claimed |
| WO-1991007236-A1 | METHOD AND APPARATUS FOR THE RAPID DEPOSITION BY CHEMICAL VAPOR DEPOSITION WITH LOW VAPOR PRESSURE REACTANTS | GEORGIA TECH RESEARCH CORPORATION (US) | 1991-05-30 | — | — | WO | claimed |
| EP-0028758-B1 | PROCESS FOR PREPARING ALKYL ESTERS AND CYCLOALKYL ESTERS OF PIVALOYL-PYRUVIC ACID | BAYER AG (DE) | 1982-12-15 | — | — | EP | claimed |
| US-9828379-B2 | Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof | ABIDE THERAPEUTICS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| US-20160137649-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. | 2016-05-19 | — | — | US | disclosed |
| EP-3016653-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | Abide Therapeutics, Inc. (US) | 2016-05-11 | — | — | EP | disclosed |
| US-9035446-B2 | Power module | FUJI ELECTRIC CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| WO-2015003002-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. (US) | 2015-01-08 | — | — | WO | disclosed |
| EP-0693473-B1 | Method of producing pivaloylacetic acid ester | UBE INDUSTRIES (JP) | 1998-04-22 | — | — | EP | disclosed |
| US-5679830-A | DECARBONYLATION OF PIVALOYLPYRUVIC ACID IN THE PRESENCE OF AN INORGANIC OXIDE CATALYST | UBE INDUSTRIES, LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0693473-A1 | Method of producing pivaloylacetic acid ester | UBE INDUSTRIES, LTD. (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5449799-A | Compound for depositing copper layers | TERFLOTH CHRISTIAN (DE) | 1995-09-12 | — | — | US | disclosed |
| EP-0028758-A1 | Process for preparing alkyl esters and cycloalkyl esters of pivaloyl-pyruvic acid | BAYER AG (DE) | 1981-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137649-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | FAAH, FAAH2, ABHD6 | OR51E2 1159/4885HAO1 2946/4885KMT2A 2502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.