Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423862 | 0.81 | MMP2 (0.53) | BCL9CTNNB1MAPTCRHBPCRHR2 | |
| SCHEMBL2387943 | 0.81 | MMP2 (0.53) | BCL9CTNNB1MAPTCRHBPCRHR2 | |
| SCHEMBL8740500 | 0.81 | MMP2 (0.53) | BCL9CTNNB1MAPTCRHBPCRHR2 | |
| SCHEMBL30864656 | 0.80 | BCL9 (0.49) | BCL9CTNNB1MAPTCRHBPCRHR2 | |
| SCHEMBL26601519 | 0.80 | BCL9 (0.49) | BCL9CTNNB1MAPTCRHBPCRHR2 | |
| SCHEMBL30864492 | 0.79 | BCL9 (0.51) | BCL9CTNNB1MAPTCRHBPCRHR2 | |
| SCHEMBL27008578 | 0.78 | BCL9 (0.45) | BCL9CTNNB1MAPTCRHBPCRHR2 | |
| SCHEMBL7275811 | 0.77 | BCL9 (0.50) | BCL9CTNNB1MAPTCRHBPCRHR2 | |
| SCHEMBL9840744 | 0.77 | BCL9 (0.50) | BCL9CTNNB1MAPTCRHBPCRHR2 | |
| SCHEMBL29400871 | 0.77 | PPARG (0.51) | BCL9CTNNB1MAPTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366685-A4 | NUCLEOSIDE DERIVATIVES | — | 1991-03-20 | — | — | EP | disclosed |
| EP-0366685-A1 | NUCLEOSIDE DERIVATIVES. | FLOREY HOWARD INST (AU) | 1990-05-09 | — | — | EP | disclosed |
| WO-1988010264-A1 | NUCLEOSIDE DERIVATIVES | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY (AU) | 1988-12-29 | — | — | WO | disclosed |