SCHEMBL2387943

SCHEMBL2387943

NCCCC[C@H](N)C(=O)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MMP2 P08253 1/20 0.53
▸ MAPT P10636 2/20 0.47
▸ CRHBP P24387 1/20 0.47
▸ CRHR2 Q13324 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ BCL9 O00512 1/20 0.46
▸ CTNNB1 P35222 1/20 0.46
▸ KMT2A Q03164 2/20 0.45
▸ PKM P14618 1/20 0.45
▸ GAA P10253 1/20 0.44
▸ MGLL Q99685 2/20 0.44
▸ HTR2A P28223 1/20 0.43
▸ MC4R P32245 1/20 0.42
▸ DPP8 Q6V1X1 1/20 0.42
▸ DPP9 Q86TI2 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.41
▸ HGFAC Q04756 1/20 0.40
▸ PDF Q9HBH1 1/20 0.40
▸ PTPN7 P35236 1/20 0.40
▸ PTPN12 Q05209 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8740500 1.00 MMP2 (0.53) MMP2MAPTCRHBPCRHR2L3MBTL1
SCHEMBL4423862 1.00 MMP2 (0.53) MMP2MAPTCRHBPCRHR2L3MBTL1
SCHEMBL28783978 0.90 MMP2 (0.49) MMP2MAPTCRHBPCRHR2L3MBTL1
SCHEMBL9840744 0.82 BCL9 (0.50) MAPTCRHBPCRHR2L3MBTL1BCL9
SCHEMBL7275811 0.82 BCL9 (0.50) MAPTCRHBPCRHR2L3MBTL1BCL9
SCHEMBL28323255 0.81 BCL9 (0.51) MAPTCRHBPCRHR2BCL9CTNNB1
SCHEMBL712246 0.81 MMP2 (0.46) MMP2MAPTKMT2AALDH1A1
SCHEMBL18941468 0.81 PDF (0.48) MMP2MAPTCRHBPCRHR2L3MBTL1
SCHEMBL18941467 0.81 PDF (0.48) MMP2MAPTCRHBPCRHR2L3MBTL1
SCHEMBL9819573 0.81 BCL9 (0.47) MMP2MAPTCRHBPCRHR2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083142-A1 DRIED FLAKES WITH ACTIVE INGREDIENTS FLAVORSENSE (US) 2026-03-26 — — US disclosed
US-12310379-B2 Dried flakes with active ingredients FLAVORSENSE (US) 2025-05-27 — — US disclosed
US-12168030-B2 Method for producing stable Actinidia deliciosa powder with high level bioactive actinidin enzyme WAITAKI BIOSCIENCES (NZ) 2024-12-17 — — US disclosed
CN-117582521-A therapeutic dendrimers 阿斯利康(瑞典)有限公司 2024-02-23 — — CN disclosed
US-20230292797-A1 DRIED FLAKES WITH ACTIVE INGREDIENTS FLAVORSENSE 2023-09-21 — — US disclosed
US-11533936-B2 Dried flakes with active ingredients FLAVORSENSE (US) 2022-12-27 — — US disclosed
EP-4099841-A1 METHOD FOR PRODUCING STABLE ACTINIDIA DELICIOSA POWDER WITH HIGH LEVEL BIOACTIVE ACTINIDIN ENZYME Waitaki Biosciences (NZ) 2022-12-14 — — EP disclosed
US-8017557-B2 Moderate protein hydrolyzates in plants ENDURA S.P.A. (IT) 2011-09-13 — — US disclosed
EP-1511382-B1 BENZODIOXOLE DERIVATIVES AS MODULATORS OF THE PROTEOLYTIC ACTIVITY IN PLANTS ENDURA SPA (IT) 2006-04-12 — — EP disclosed
US-20050085390-A1 Benzodioxole derivatives as modulators of proteolytic activity in plants ENDURA S.P.A. (IT) 2005-04-21 — — US disclosed
EP-1511382-A1 BENZODIOXOLE DERIVATIVES AS MODULATORS OF THE PROTEOLYTIC ACTIVITY IN PLANTS ENDURA S.p.A. (IT) 2005-03-09 — — EP disclosed
WO-2003067985-A1 BENZODIOXOLE DERIVATIVES AS MODULATORS OF THE PROTEOLYTIC ACTIVITY IN PLANTS ENDURA S.P.A. (IT) 2003-08-21 — — WO disclosed
EP-0636028-A4 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM. UNIV CALIFORNIA (US) 1998-12-09 — — EP disclosed
EP-0715619-A4 INHIBITORS OF TNF-ALPHA SECRETION IMMUNEX CORP (US) 1997-03-19 — — EP disclosed
EP-0715619-A1 INHIBITORS OF TNF-ALPHA SECRETION IMMUNEX CORPORATION (US) 1996-06-12 — — EP disclosed
EP-0636028-A1 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-02-01 — — EP disclosed
WO-1993019768-A1 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-10-14 — — WO disclosed
EP-0002677-B1 GLUCOSAMINE-PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICAL COMPOSITIONS Takeda Chemical Industries, Ltd. (JP) 1982-10-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083142-A1 DRIED FLAKES WITH ACTIVE INGREDIENTS COG1, COG5, COG3 MMP2 3689/4885MAPT 445/4885CRHBP 3714/4885
US-20050085390-A1 Benzodioxole derivatives as modulators of proteolytic activity in plants BBOX1, BROX, PEPD MMP2 20/4885MAPT 3823/4885CRHBP 1644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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