Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8701149 | 0.99 | CYP19A1 (0.39) | CYP19A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8698749 | 0.80 | HMOX1 (0.41) | CYP19A1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL8539485 | 0.76 | HRH3 (0.51) | — | |
| Hydrochloric Acid SCHEMBL8541843 | 0.75 | HRH3 (0.50) | — | |
| SCHEMBL8701879 | 0.74 | ALDH1A1 (0.37) | LMNAMAPTALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8701141 | 0.74 | ALDH1A1 (0.36) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8545347 | 0.74 | SIGMAR1 (0.53) | — | |
| SCHEMBL6648239 | 0.72 | CYP19A1 (0.62) | CYP19A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9820752 | 0.72 | PLG (0.40) | PLG | |
| SCHEMBL9820857 | 0.71 | CCR3 (0.41) | PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |