Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821551 | 1.00 | POLB (0.48) | POLBGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9821384 | 0.80 | HPGD (0.43) | POLBGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9821376 | 0.78 | GAA (0.60) | POLBGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9821379 | 0.78 | GAA (0.60) | POLBGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9821458 | 0.77 | AMY1A (0.41) | POLBGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6695867 | 0.73 | CYP3A4 (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4956254 | 0.69 | POLB (0.57) | POLBGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL5310267 | 0.68 | GAA (0.59) | POLBGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL17712851 | 0.65 | GRIN2D (0.61) | POLBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17712848 | 0.65 | GRIN2D (0.61) | POLBGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041458-A | Fungicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0349580-B1 | FUNGICIDAL AMINOTRIAZOLES AND AMINOIMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| EP-0349580-A1 | FUNGICIDAL AMINOTRIAZOLES AND AMINOIMIDAZOLES. | DU PONT (US) | 1990-01-10 | — | — | EP | disclosed |
| WO-1988007040-A1 | FUNGICIDAL AMINOTRIAZOLES AND AMINOIMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-22 | — | — | WO | disclosed |
| EP-0283245-A1 | Fungicidal aminotriazoles and aminoimidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-21 | — | — | EP | disclosed |