Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821551 | 0.80 | POLB (0.48) | HPGDKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL9821549 | 0.80 | POLB (0.48) | HPGDKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL9821458 | 0.72 | AMY1A (0.41) | HPGDKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL9821379 | 0.70 | GAA (0.60) | HPGDKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL9821376 | 0.70 | GAA (0.60) | HPGDKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL9821500 | 0.65 | POLB (0.35) | HPGDKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL13008512 | 0.63 | HSPB1 (0.42) | ALDH1A1 | |
| SCHEMBL6764191 | 0.63 | CA3 (0.38) | ALDH1A1 | |
| SCHEMBL4956254 | 0.62 | POLB (0.57) | HPGDKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL9821386 | 0.62 | CYP19A1 (0.34) | ALDH1A1POLBGAAKMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349580-B1 | FUNGICIDAL AMINOTRIAZOLES AND AMINOIMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |