SCHEMBL982200

SCHEMBL982200

Cc1cc[c]c(-c2ccccc2)c1C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
CYP2A6 P11509 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33
CYP2B6 P20813 1/20 0.33
TSHR P16473 3/20 0.32
ACHE P22303 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
ESR2 Q92731 1/20 0.31
CYP1A2 P05177 1/20 0.31
LMNA P02545 1/20 0.31
ALOX12 P18054 1/20 0.31
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5779381 0.83 ACHE (0.35) ACHE
SCHEMBL15067739 0.81 TRPA1 (0.31)
SCHEMBL7070227 0.81 BRD4 (0.36) ALDH1A1CYP2A6KMT2AKDM4EPOLB
SCHEMBL11722875 0.77 NPC1 (0.36) ALDH1A1CYP2A6PKMRAB9ATSHR
SCHEMBL10769045 0.77 RXRA (0.31)
SCHEMBL12815393 0.76 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL981110 0.76 TSHR (0.39) ALDH1A1CYP2A6RAB9ACYP2B6TSHR
SCHEMBL8074720 0.75 NOTUM (0.35) ALDH1A1MAPTRAB9ATSHR
SCHEMBL2349974 0.75 CYP2A6 (0.42) ALDH1A1CYP2A6TSHR
SCHEMBL6699053 0.74 TRPA1 (0.38) ALDH1A1CYP2A6MAPTTSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322195-A Compound and application thereof 北京鼎材科技有限公司 2022-11-11 CN claimed
US-6846619-B2 Dye dispersion liquid and thermosensitive recording material using the same RICOH COMPANY, LTD. (JP) 2005-01-25 US claimed
EP-1243437-B1 Leuco dye dispersion liquid and thermosensitive recording material using the same RICOH KK (JP) 2004-11-17 EP claimed
EP-1171222-B1 PROCESS FOR REMOVING HYDROGEN SULFIDE FROM GASES CRYSTATECH INC (US) 2004-09-01 EP claimed
US-20030060366-A1 Dye dispersion liquid and thermosensitive recording material using the same RICOH COMPANY, LTD. 2003-03-27 US claimed
EP-1243437-A1 Leuco dye dispersion liquid and thermosensitive recording material using the same Ricoh Company, Ltd. (JP) 2002-09-25 EP claimed
US-6010743-A FORMING POLYURETHANES ELF ATOCHEM S.A. (FR) 2000-01-04 US claimed
EP-3560900-B1 SEALING MATERIAL FOR MULTI-LAYERED GLASSES, AND MULTI-LAYERED GLASS DAINIPPON INK & CHEMICALS (JP) 2023-08-30 EP disclosed
CN-115448956-A Molecular arrangement of homoleptic iridium phosphors 南加州大学 2022-12-09 CN disclosed
CN-115322195-A Compound and application thereof 北京鼎材科技有限公司 2022-11-11 CN disclosed
CN-110099878-B Sealing material for laminated glass and laminated glass DIC株式会社 2021-12-14 CN disclosed
US-10982123-B2 Sealing material for multi-layered glasses, and multi-layered glass DIC CORPORATION (JP) 2021-04-20 US disclosed
US-20200040239-A1 SEALING MATERIAL FOR MULTI-LAYERED GLASSES, AND MULTI-LAYERED GLASS DIC CORPORATION (JP) 2020-02-06 US disclosed
US-6416729-B1 ADDING SULFUR DIOXIDE TO A HYDROGEN SULFIDE REMOVAL SYSTEM (COMPRISED OF TERTIARY AMINE IN A SOLVENT SUCH AS PHENYLXYLYL ETHANE) TO IMPROVE REMOVAL; IMPROVEMENT OVER CLAUS PROCESS AND SULFUR-AMINE NONAQUEOUS SORBENTS (SANS) PROCESS CRYSTATECH, INC. 2002-07-09 US disclosed
EP-1051394-A1 POTASSIUM CHANNEL INHIBITORS Icagen, Inc. (US) 2000-11-15 EP disclosed
WO-1999037607-A1 POTASSIUM CHANNEL INHIBITORS ICAGEN, INC. (US) 1999-07-29 WO disclosed
US-4806552-A ANTIDEPRESSANTS JOHN WYETH & BROTHER, LIMITED (GB) 1989-02-21 US disclosed
US-4656221-A SOLVENT-FREE POLYSILOXANE COATINGS; RADIATION TRANSPARENT FOR USE ON COLORLESS BEVERAGE BOTTLES TOSHIBA SILICONE CO., LTD. (JP) 1987-04-07 US disclosed
US-4420791-A Dielectric fluid EMHART INDUSTRIES, INC. (US) 1983-12-13 US disclosed
EP-0012107-B1 FLAME-RETARDANT PLASTIFIED PVC-COMPOSITION CIBA-GEIGY AG (CH) 1983-06-22 EP disclosed