Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982200 | 0.83 | ALDH1A1 (0.33) | ACHE | |
| SCHEMBL15067739 | 0.81 | TRPA1 (0.31) | — | |
| SCHEMBL10769045 | 0.81 | RXRA (0.31) | — | |
| SCHEMBL8074720 | 0.79 | NOTUM (0.35) | TDP1 | |
| SCHEMBL2349974 | 0.79 | CYP2A6 (0.42) | — | |
| SCHEMBL5850268 | 0.76 | HSD17B10 (0.46) | ACHETDP1 | |
| SCHEMBL11696260 | 0.75 | HSD11B1 (0.42) | — | |
| SCHEMBL3346134 | 0.74 | ACHE (0.35) | ACHETDP1 | |
| SCHEMBL2834322 | 0.71 | PTGS2 (0.35) | ACHETDP1 | |
| SCHEMBL10570766 | 0.71 | HPGD (0.35) | ACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615890-A1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | WARNER-LAMBERT COMPANY (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089903-A1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-21 | — | — | WO | disclosed |