Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.42 |
| ▸ | RARG | P13631 | 5/20 | 0.42 |
| ▸ | RARA | P10276 | 4/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822486 | 0.81 | RARB (0.66) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9822570 | 0.81 | RARB (0.55) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9746735 | 0.80 | RARB (0.63) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL10544739 | 0.79 | RARB (0.48) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9746813 | 0.79 | RARB (0.43) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9746239 | 0.77 | PTPN11 (0.48) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9748837 | 0.77 | CYP26B1 (0.46) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8522801 | 0.73 | RXRA (0.60) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL10335828 | 0.72 | ALDH1A1 (0.49) | GAAALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL10335262 | 0.72 | KDM4E (0.50) | GAAALDH1A1KDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297995-B1 | POLYCYCLIC AROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND ANIMAL MEDICINE AND IN COSMETICS | L'OREAL (FR) | 1991-03-06 | — | — | EP | claimed |
| US-4980509-A | Aromatic polycyclic derivatives, their process of preparation and their use in human and veterinary medicine and in cosmetics | SOCIETE ANONYME DITE: L'OREAL (FR) | 1990-12-25 | — | — | US | claimed |
| US-4980509-A | Aromatic polycyclic derivatives, their process of preparation and their use in human and veterinary medicine and in cosmetics | SOCIETE ANONYME DITE: L'OREAL (FR) | 1990-12-25 | — | — | US | disclosed |