Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822480 | 0.84 | PTGS2 (0.40) | PTGS2AKR1C3 | |
| SCHEMBL9822454 | 0.76 | MAOB (0.59) | PTGS2AKR1C3 | |
| SCHEMBL9822447 | 0.76 | MAOB (0.59) | PTGS2AKR1C3 | |
| SCHEMBL9822422 | 0.69 | RXRA (0.49) | — | |
| SCHEMBL9822439 | 0.67 | RARA (0.47) | PTGS2AKR1C3 | |
| SCHEMBL9822581 | 0.67 | RARA (0.47) | PTGS2AKR1C3 | |
| SCHEMBL4407340 | 0.66 | RXRA (0.48) | — | |
| SCHEMBL9822364 | 0.66 | RARB (0.42) | — | |
| SCHEMBL9822462 | 0.65 | RXRA (0.34) | AKR1C3 | |
| SCHEMBL9822434 | 0.65 | RXRA (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297995-B1 | POLYCYCLIC AROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND ANIMAL MEDICINE AND IN COSMETICS | L'OREAL (FR) | 1991-03-06 | — | — | EP | claimed |