Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97864 | 0.79 | PPARG (0.49) | PPARGKDM4EFFAR1HSD17B10ALDH1A1 | |
| SCHEMBL97465 | 0.79 | FFAR1 (0.46) | PPARGKDM4EFFAR1HSD17B10ALDH1A1 | |
| SCHEMBL8685380 | 0.77 | CA2 (0.43) | CA2PPARGMAOACISD1FFAR1 | |
| SCHEMBL29249872 | 0.76 | KDM4E (0.54) | KDM4ENQO2HSD17B10ALDH1A1NPSR1 | |
| SCHEMBL31092665 | 0.76 | KDM4E (0.54) | KDM4ENQO2HSD17B10ALDH1A1NPSR1 | |
| SCHEMBL19719694 | 0.76 | KDM4E (0.61) | KDM4ENQO2HSD17B10ALDH1A1MAPT | |
| SCHEMBL13846729 | 0.75 | DDB1 (0.56) | CA2PPARGMAOACISD1DDB1 | |
| SCHEMBL8809908 | 0.75 | MAPT (0.40) | CA2PPARGMAOACISD1FFAR1 | |
| SCHEMBL8685503 | 0.75 | HTR6 (0.49) | CA2PPARGFFAR1MAOBMAPT | |
| SCHEMBL8809537 | 0.75 | ICMT (0.41) | CA2PPARGMAOACISD1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | claimed |