Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12291744 | 0.89 | KMT2A (0.75) | KMT2AMEN1OPRK1SMN1; SMN2HSD17B10 | |
| SCHEMBL27476119 | 0.86 | OPRK1 (0.66) | KMT2AMEN1OPRK1SMN1; SMN2HSD17B10 | |
| Acetaminophen SCHEMBL28082151 | 0.86 | MAPT (0.61) | KMT2AMEN1OPRK1SMN1; SMN2HSD17B10 | |
| SCHEMBL10713248 | 0.86 | RAB9A (0.63) | KMT2AMEN1OPRK1SMN1; SMN2LMNA | |
| SCHEMBL1930736 | 0.86 | KMT2A (0.70) | KMT2AMEN1OPRK1SMN1; SMN2HSD17B10 | |
| SCHEMBL668622 | 0.84 | KMT2A (0.68) | KMT2AMEN1OPRK1SMN1; SMN2HSD17B10 | |
| SCHEMBL12987121 | 0.84 | KMT2A (0.68) | KMT2AMEN1OPRK1SMN1; SMN2HSD17B10 | |
| SCHEMBL12291743 | 0.84 | KMT2A (0.68) | KMT2AMEN1OPRK1SMN1; SMN2HSD17B10 | |
| SCHEMBL3805817 | 0.84 | KMT2A (0.68) | KMT2AMEN1OPRK1SMN1; SMN2HSD17B10 | |
| SCHEMBL10329430 | 0.83 | OPRK1 (0.62) | KMT2AMEN1OPRK1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| CN-101318886-B | Process for synthesizing o-hydroxyl-phenyl-alkyl ketone | UNIV ZHEJIANG SCIENCE & TECH | 2011-05-04 | — | — | CN | disclosed |
| CN-101318886-A | Process for synthesizing o-hydroxyl-phenyl-alkyl ketone | UNIV ZHEJIANG SCIENCE & TECH (CN) | 2008-12-10 | — | — | CN | disclosed |
| US-7442826-B2 | Process for the preparation of nitrooxyderivatives of paracetamol | NICOX S.A. (FR) | 2008-10-28 | — | — | US | disclosed |
| EP-0220746-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4783396-A | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0220746-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |