Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824463 | 1.00 | KDM4E (0.36) | KDM4EALDH1A1TSHRHTTMEN1 | |
| SCHEMBL9824184 | 0.98 | KDM4E (0.37) | KDM4EALDH1A1TSHRHTTMEN1 | |
| SCHEMBL9824265 | 0.94 | TSHR (0.38) | KDM4EALDH1A1TSHRHTTPABPC1 | |
| SCHEMBL9824067 | 0.87 | TSHR (0.42) | KDM4EALDH1A1TSHRMEN1NPC1 | |
| SCHEMBL9823744 | 0.84 | MEN1 (0.49) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9823926 | 0.83 | KDM4E (0.35) | KDM4EALDH1A1TSHRHTR1ADRD2 | |
| SCHEMBL14359278 | 0.83 | HTR1A (0.36) | KDM4EALDH1A1TSHRHTR1ADRD2 | |
| SCHEMBL11057614 | 0.83 | TSHR (0.36) | KDM4EALDH1A1TSHRHTR1ADRD2 | |
| SCHEMBL9823908 | 0.82 | ALDH1A1 (0.39) | KDM4EALDH1A1TSHRHTTMEN1 | |
| SCHEMBL9824052 | 0.82 | MEN1 (0.47) | KDM4EALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |