Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16038492 | 0.85 | CHRM2 (0.36) | KMT2AKDM4EMEN1HTR1ADRD2 | |
| SCHEMBL9824463 | 0.82 | KDM4E (0.36) | ALDH1A1HTTPABPC1KMT2AKDM4E | |
| SCHEMBL9823819 | 0.82 | KDM4E (0.36) | ALDH1A1HTTPABPC1KMT2AKDM4E | |
| SCHEMBL26180438 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HTTPABPC1KMT2AKDM4E | |
| SCHEMBL9823770 | 0.80 | PTGS1 (0.47) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL9824184 | 0.80 | KDM4E (0.37) | ALDH1A1HTTPABPC1KMT2AKDM4E | |
| SCHEMBL14359588 | 0.79 | HTR1A (0.36) | SMN1; SMN2HTR1ADRD2HTR2CHTR7 | |
| SCHEMBL19062108 | 0.76 | HTR1A (0.34) | KMT2AKDM4EMEN1RECQLHTR1A | |
| SCHEMBL8283007 | 0.76 | CHRM2 (0.41) | ALDH1A1KMT2AMEN1HTR1ADRD2 | |
| SCHEMBL9824265 | 0.75 | TSHR (0.38) | ALDH1A1HTTPABPC1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |