Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756056 | 0.81 | PPARD (0.36) | ALDH1A1L3MBTL1MAPTGAATHRB | |
| SCHEMBL755872 | 0.80 | TBXA2R (0.42) | ALDH1A1MAPK1MAPTHTTPPARD | |
| SCHEMBL1417730 | 0.79 | KDM4E (0.49) | ALDH1A1L3MBTL1MAPK1MAPTHTT | |
| SCHEMBL8643566 | 0.79 | HSPB1 (0.51) | S1PR4HSPB1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL17186845 | 0.77 | HSPB1 (0.54) | S1PR4HSPB1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL12004049 | 0.77 | KDR (0.44) | HSPB1ALDH1A1L3MBTL1MAPK1MAPT | |
| SCHEMBL1417566 | 0.76 | PPARA (0.56) | ALDH1A1MAPTPPARDPPARAPPARG | |
| SCHEMBL4379631 | 0.76 | RECQL (0.54) | S1PR4HSPB1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL4002337 | 0.75 | PPARD (0.63) | ALDH1A1MAPTGAAPPARDPSEN1 | |
| SCHEMBL1641896 | 0.75 | ALDH1A1 (0.44) | S1PR4HSPB1ALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718817-B2 | Aryl and heteroaryl ether compounds as ROR gamma modulators | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-08-01 | — | — | US | disclosed |
| WO-2017051319-A1 | ARYL AND HETEROARYL ETHER COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-03-30 | — | — | WO | disclosed |
| EP-3131880-A1 | ARYL AND HETEROARYL ETHER COMPOUNDS AS ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2017-02-22 | — | — | EP | disclosed |
| US-20170022195-A1 | ARYL AND HETEROARYL ETHER COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-01-26 | — | — | US | disclosed |
| WO-2015159233-A1 | ARYL AND HETEROARYL ETHER COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-10-22 | — | — | WO | disclosed |
| EP-0142328-B1 | FLUOROPHENOXY COMPOUNDS, HERBICIDAL COMPOSITIONS AND METHODS | THE DOW CHEMICAL COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4888050-A | GRASS CONTROL | THE DOW CHEMICAL COMPANY (US) | 1989-12-19 | — | — | US | disclosed |
| US-4750931-A | GRASSY WEEDS | THE DOW CHEMICAL COMPANY (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0142328-A2 | Fluorophenoxy compounds, herbicidal compositions and methods | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022195-A1 | ARYL AND HETEROARYL ETHER COMPOUNDS AS ROR GAMMA MODULATORS | RORB, RORA, RORC | S1PR4 1021/4885HSPB1 1112/4885ALDH1A1 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.