SCHEMBL9825283

SCHEMBL9825283

COc1ccccc2cc3sccc3c1-2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA12 O43570 1/20 0.39
CA4 P22748 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CTSA P10619 1/20 0.38
HTR1A P08908 2/20 0.38
HTR7 P34969 2/20 0.38
MEN1 O00255 1/20 0.37
TNF P01375 1/20 0.37
KMT2A Q03164 1/20 0.37
NOD1 Q9Y239 1/20 0.37
MAPT P10636 2/20 0.37
HSP90AA1 P07900 1/20 0.37
ERN1 O75460 1/20 0.36
CTNNB1 P35222 1/20 0.36
WNT3A P56704 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9825060 0.77 NEK1 (0.40) CTSAALDH1A1
SCHEMBL9825138 0.77 NEK1 (0.40) ERN1
SCHEMBL827010 0.71 CA2 (0.44) CA1CA2CA7CA9CA12
SCHEMBL9825922 0.70 MAPT (0.41) CA1CA2CA7CA9CA12
SCHEMBL30865706 0.69 HTR1A (0.58) CA1CA2CA7CA9CA12
SCHEMBL16010332 0.68 TUBB4A (0.47) CA9MAPTTSHRALDH1A1TUBB4A
SCHEMBL5758557 0.68 MAPT (0.43) CA1CA2CA7CA9CA12
SCHEMBL9749622 0.67 ALOX5 (0.46) ALOX5RORB
SCHEMBL28744577 0.67 CA2 (0.44) CA1CA2CA7CA9CA12
SCHEMBL26259629 0.66 MAPT (0.52) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037575-A Photostability MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1991-08-06 US disclosed
EP-0187015-B1 SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME MITSUBISHI KASEI CORPORATION (JP) 1991-05-29 EP disclosed