Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824783 | 0.80 | LMNA (0.36) | PTPN5HDAC8KDM4EALDH1A1TP53 | |
| SCHEMBL9826641 | 0.78 | ACHE (0.38) | KDM4EALDH1A1TP53MAPTHPGD | |
| SCHEMBL9824974 | 0.74 | RXRA (0.36) | RXRARXRBRXRGPTPN5HDAC4 | |
| SCHEMBL9825028 | 0.73 | XDH (0.38) | HDAC4HDAC8CA2MAPTSMN1; SMN2 | |
| SCHEMBL9824842 | 0.71 | PPARG (0.40) | RXRARXRBRXRGPTPN5HDAC4 | |
| SCHEMBL9826546 | 0.71 | RXRA (0.36) | RXRARXRBRXRGPTPN5HDAC4 | |
| SCHEMBL9177215 | 0.69 | RXRA (0.50) | RXRARXRBRXRGPTPN5HDAC4 | |
| SCHEMBL9879887 | 0.68 | SREBF2 (0.41) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9824769 | 0.68 | RXRA (0.40) | RXRARXRBRXRGPTPN5HDAC4 | |
| SCHEMBL5352034 | 0.68 | RXRA (0.62) | RXRARXRBRXRGPTPN5HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0187015-B1 | SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1991-05-29 | — | — | EP | disclosed |
| EP-0187015-A2 | Squarilium compound and liquid crystal composition containing the same | MITSUBISHI KASEI CORPORATION (JP) | 1986-07-09 | — | — | EP | disclosed |