Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826339 | 0.80 | LMNA (0.36) | KDM4EMAPTTYRHPGDSMN1; SMN2 | |
| SCHEMBL9825320 | 0.78 | SLC9A1 (0.38) | ADRA2AADRA2BKDM4EALDH1A1CA9 | |
| SCHEMBL9825362 | 0.74 | RXRA (0.36) | RXRARXRBRXRGHDAC4HDAC8 | |
| SCHEMBL22479801 | 0.74 | METAP2 (0.49) | ADRA2BMAPTHPGDCTSAALOX5 | |
| SCHEMBL9749622 | 0.73 | ALOX5 (0.46) | ADRA2AADRA2BALOX5 | |
| SCHEMBL9874491 | 0.73 | CNR2 (0.41) | ALDH1A1MAPTHPGDSMN1; SMN2CA9 | |
| SCHEMBL9825060 | 0.73 | NEK1 (0.40) | HDAC4HDAC8ALDH1A1CTSANEK1 | |
| SCHEMBL9824842 | 0.71 | PPARG (0.40) | RXRARXRBRXRGHDAC4HDAC8 | |
| SCHEMBL9826546 | 0.71 | RXRA (0.36) | RXRARXRBRXRGHDAC4HDAC8 | |
| SCHEMBL9177215 | 0.69 | RXRA (0.50) | RXRARXRBRXRGHDAC4HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0187015-B1 | SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1991-05-29 | — | — | EP | disclosed |
| EP-0187015-A2 | Squarilium compound and liquid crystal composition containing the same | MITSUBISHI KASEI CORPORATION (JP) | 1986-07-09 | — | — | EP | disclosed |