Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 12/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | MOGAT2 | Q3SYC2 | 4/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826520 | 0.89 | CNR2 (0.34) | MOGAT2 | |
| SCHEMBL9826088 | 0.87 | L3MBTL1 (0.34) | DRD3DRD2MOGAT2 | |
| SCHEMBL9827149 | 0.87 | ALDH1A1 (0.37) | DRD3DRD2MOGAT2GRIN2BGRIN1 | |
| SCHEMBL9826326 | 0.86 | DRD3 (0.35) | DRD3MOGAT2GRIN2BMGAT2 | |
| SCHEMBL9825575 | 0.85 | ALDH1A1 (0.39) | MOGAT2GRIN2BGRIN1 | |
| SCHEMBL9825690 | 0.85 | ALDH1A1 (0.39) | DRD3DRD2MOGAT2 | |
| SCHEMBL9827456 | 0.84 | ALDH1A1 (0.39) | DRD3DRD2 | |
| SCHEMBL9825542 | 0.84 | SMN1; SMN2 (0.37) | MOGAT2 | |
| SCHEMBL9827236 | 0.83 | ALDH1A1 (0.45) | — | |
| SCHEMBL9826186 | 0.83 | HRH3 (0.36) | MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239815-B1 | SUBSTITUTED THIAZOLES AND OXAZOLES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1991-07-24 | — | — | EP | disclosed |
| EP-0239815-A1 | Substituted thiazoles and oxazoles, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1987-10-07 | — | — | EP | disclosed |