Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825799 | 0.79 | SIGMAR1 (0.51) | SIGMAR1PARP1DRD4DRD2DRD3 | |
| SCHEMBL9826050 | 0.79 | KCNA3 (0.55) | SIGMAR1PARP1DRD4DRD2DRD3 | |
| SCHEMBL2483050 | 0.79 | TDP1 (0.64) | RAB9AMAPTNPC1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9826723 | 0.78 | KCNA3 (0.54) | SIGMAR1PARP1DRD4DRD2DRD3 | |
| SCHEMBL2486394 | 0.78 | HRH3 (0.64) | RAB9AMAPTNPC1LMNASMN1; SMN2 | |
| SCHEMBL2481096 | 0.76 | KDM4E (0.53) | RAB9AMAPTNPC1LMNASMN1; SMN2 | |
| SCHEMBL9825205 | 0.75 | HTR1A (0.68) | MAPTDRD4DRD2DRD3HTR1A | |
| SCHEMBL2485756 | 0.75 | TDP1 (0.58) | RAB9AMAPTNPC1LMNASMN1; SMN2 | |
| SCHEMBL9826692 | 0.75 | DRD2 (0.55) | RAB9ANPC1DRD2DRD3HTR1A | |
| SCHEMBL6162058 | 0.74 | SIGMAR1 (0.60) | SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237781-B1 | PHENYL AND HETEROCYCLIC TETRAHYDROPYRIDYL AND PIPERAZINYL ALKOXY-BENZHETEROCYCLIC COMPOUNDS AS ANTIPSYCHOTIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1991-04-24 | — | — | EP | claimed |