Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826876 | 0.94 | TP53 (0.34) | — | |
| SCHEMBL9826951 | 0.91 | FAAH (0.37) | CNR1 | |
| SCHEMBL9457272 | 0.90 | CTSK (0.34) | NAAAMEN1KMT2ACTSKHDAC4 | |
| SCHEMBL9457276 | 0.90 | CTSK (0.34) | NAAAMEN1KMT2ACTSKHDAC4 | |
| SCHEMBL9457286 | 0.90 | CTSK (0.34) | NAAAMEN1KMT2ACTSKHDAC4 | |
| SCHEMBL9456952 | 0.88 | MEN1 (0.36) | NAAAMEN1KMT2ACTSKMMP1 | |
| SCHEMBL9649923 | 0.85 | GPR84 (0.41) | MEN1KMT2AMMP1MMP3 | |
| SCHEMBL9457193 | 0.85 | GPR84 (0.41) | MEN1KMT2AMMP1MMP3 | |
| SCHEMBL9457368 | 0.85 | GPR84 (0.41) | MEN1KMT2AMMP1MMP3 | |
| SCHEMBL9457380 | 0.85 | GPR84 (0.41) | MEN1KMT2AMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185359-B1 | OXETANONE | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-04 | — | — | EP | disclosed |
| EP-0189577-A2 | Process for the preparation of oxetanones | F. HOFFMANN-LA ROCHE AG (CH) | 1986-08-06 | — | — | EP | disclosed |
| EP-0185359-A2 | Oxetanone | F. HOFFMANN-LA ROCHE AG (CH) | 1986-06-25 | — | — | EP | disclosed |