Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826951 | 0.97 | FAAH (0.37) | MAPT | |
| SCHEMBL9825859 | 0.94 | NAAA (0.35) | — | |
| SCHEMBL9825863 | 0.91 | DGKA (0.35) | TP53CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL9825662 | 0.90 | KDM4E (0.37) | — | |
| SCHEMBL9827120 | 0.89 | FAAH (0.37) | — | |
| SCHEMBL10872979 | 0.88 | FAAH (0.38) | MAPT | |
| SCHEMBL9457388 | 0.87 | FFAR1 (0.39) | CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL9457366 | 0.87 | FFAR1 (0.39) | CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL9457402 | 0.87 | FFAR1 (0.39) | CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL9457394 | 0.87 | FFAR1 (0.39) | CYP1A2MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185359-B1 | OXETANONE | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-04 | — | — | EP | disclosed |