Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825662 | 0.91 | KDM4E (0.37) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL9825863 | 0.91 | DGKA (0.35) | DGKAFFAR1FFAR4 | |
| SCHEMBL9457356 | 0.90 | FFAR1 (0.41) | DGKAFFAR1FFAR4 | |
| SCHEMBL9457411 | 0.90 | FFAR1 (0.41) | DGKAFFAR1FFAR4 | |
| SCHEMBL9457344 | 0.90 | FFAR1 (0.41) | DGKAFFAR1FFAR4 | |
| SCHEMBL9457408 | 0.90 | FFAR1 (0.41) | DGKAFFAR1FFAR4 | |
| SCHEMBL9826321 | 0.88 | MGLL (0.39) | — | |
| SCHEMBL9827120 | 0.88 | FAAH (0.37) | — | |
| SCHEMBL9457270 | 0.88 | NFKB1 (0.40) | KDM4EALDH1A1TDP1FFAR1FFAR4 | |
| SCHEMBL9457278 | 0.88 | NFKB1 (0.40) | KDM4EALDH1A1TDP1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185359-B1 | OXETANONE | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-04 | — | — | EP | disclosed |
| EP-0185359-A2 | Oxetanone | F. HOFFMANN-LA ROCHE AG (CH) | 1986-06-25 | — | — | EP | disclosed |