Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824856 | 0.90 | ACLY (0.44) | ACLYMAOBMALT1MTNR1ALMNA | |
| SCHEMBL9826628 | 0.82 | MEN1 (0.47) | MTNR1ALMNAMEN1KMT2AAIMP2 | |
| SCHEMBL10513345 | 0.82 | MEN1 (0.32) | ACLYMAOBMEN1KMT2A | |
| SCHEMBL9690306 | 0.79 | LMNA (0.42) | ACLYMALT1MTNR1ALMNAPOLB | |
| SCHEMBL9825561 | 0.78 | CA2 (0.48) | — | |
| SCHEMBL11025933 | 0.75 | MEN1 (0.48) | MTNR1ALMNAMEN1KMT2AAIMP2 | |
| SCHEMBL11213080 | 0.73 | MEN1 (0.38) | LMNAMEN1KMT2AAIMP2MAPT | |
| SCHEMBL8795201 | 0.73 | GAA (0.45) | LMNAPOLBMEN1KMT2AMAPT | |
| SCHEMBL9824715 | 0.72 | CA2 (0.60) | — | |
| SCHEMBL9544977 | 0.71 | CA2 (0.40) | TP53MEN1KMT2ASIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | disclosed |
| EP-0252005-A1 | Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |