Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | MAX | P61244 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748698 | 0.74 | LMNA (0.48) | KMT2AMAPTL3MBTL1 | |
| SCHEMBL9260455 | 0.72 | MAPT (0.43) | KMT2AMAPTL3MBTL1 | |
| SCHEMBL5147348 | 0.69 | KMT2A (0.47) | KMT2AMAPTL3MBTL1 | |
| SCHEMBL21387269 | 0.69 | MAPT (0.41) | KMT2AMAPTL3MBTL1 | |
| SCHEMBL8726551 | 0.68 | MAPT (0.71) | KMT2AMAPTL3MBTL1CYP19A1MYC | |
| SCHEMBL8726371 | 0.68 | KMT2A (0.54) | KMT2AMAPTL3MBTL1CYP19A1 | |
| SCHEMBL24740948 | 0.65 | AMY1A (0.39) | AMY1AMAOAMAOBCYP19A1MYC | |
| SCHEMBL13879443 | 0.64 | KMT2A (0.53) | KMT2AMAPT | |
| SCHEMBL8898505 | 0.63 | KMT2A (0.42) | KMT2AMAPTL3MBTL1 | |
| SCHEMBL9787326 | 0.63 | TSHR (0.60) | KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440670-A1 | HETEROCYCLIC ACETYLENIC AMINES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY. | UPJOHN CO (US) | 1991-08-14 | — | — | EP | disclosed |