SCHEMBL8898505

SCHEMBL8898505

COC(CCN1C(=O)NC(C)C1=O)OC

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.42
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5147348 0.72 KMT2A (0.47) KMT2AMAPTL3MBTL1
SCHEMBL8726371 0.71 KMT2A (0.54) KMT2AMAPTL3MBTL1
SCHEMBL4748698 0.69 LMNA (0.48) KMT2AMAPTL3MBTL1
SCHEMBL9260455 0.67 MAPT (0.43) KMT2AMAPTL3MBTL1
SCHEMBL10964353 0.65 ALDH1A1 (0.31)
SCHEMBL21387269 0.64 MAPT (0.41) KMT2AMAPTL3MBTL1
SCHEMBL8160533 0.63 PLA2G7 (0.46) KMT2AMAPT
SCHEMBL9826491 0.63 KMT2A (0.40) KMT2AMAPTL3MBTL1
SCHEMBL14687100 0.62 CMA1 (0.60) KMT2AMAPTL3MBTL1
SCHEMBL14687062 0.62 CMA1 (0.60) KMT2AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0807267-A1 CROSSLINKED POLYMERS CONTAINING URETHANE GROUPS Novartis AG (CH) 1997-11-19 EP disclosed
WO-1996024073-A1 CROSSLINKED POLYMERS CONTAINING URETHANE GROUPS NOVARTIS AG (CH) 1996-08-08 WO disclosed